(19)

(11)

EP 1 180 240 A1

(12)

(43) Date of publication: 20.02.2002 Bulletin 2002/08 (21) Application number: 00930168.0 (22) Date of filing: 27.04.2000

(51) International Patent Classification (IPC)7: G01N 33/53, G01N 33/543, G01N 33/566 (86) International application number: PCT/US0011/270 (87) International publication number: WO 0065/350 (02.11.2000 Gazette 2000/44)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 27.04.1999 US 131151 P 07.06.1999 US 139431 P (71) Applicant: Mirus Corporation Madison, WI 53711 (US)	(72) Inventor: WOLFF, Jon, A. Madison, WI 53705 (US) (74) Representative: Van Someren, Petronella F. H. M.  Arnold & Siedsma, Advocaten en Octrooigemachtigden, Sweelinckplein 1 2517 GK Den Haag 2517 GK Den Haag (NL)