(19)

(11)

EP 1 181 301 A1

(12)

(43) Date of publication: 27.02.2002 Bulletin 2002/09 (21) Application number: 00926516.6 (22) Date of filing: 08.05.2000

(51) International Patent Classification (IPC)7: C07H 19/04, C07H 21/00 (86) International application number: PCT/US0012/530 (87) International publication number: WO 0075/157 (14.12.2000 Gazette 2000/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 03.06.1999 US 325055 (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-3500 (US)	(72) Inventor: WANG, Xiu, C. Green Oaks, IL 60064-6050 (US) (74) Representative: Modiano, Guido, Dr.-Ing. et al Modiano, Josif, Pisanty & Staub, Baaderstrasse 3 80469 München 80469 München (DE)