(19)
(11) EP 1 181 305 A1

(12)

(43) Date of publication:
27.02.2002 Bulletin 2002/09

(21) Application number: 00946758.0

(22) Date of filing: 04.05.2000
(51) International Patent Classification (IPC)7C07H 21/02, C07H 21/04, A01N 61/00
(86) International application number:
PCT/US0012/133
(87) International publication number:
WO 0071/560 (30.11.2000 Gazette 2000/48)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 20.05.1999 US 134973 P
07.06.1999 US 137837 P
14.06.1999 US 139095 P

(71) Applicants:
  • SmithKline Beecham Corporation
    Philadelphia, PA 19103 (US)
  • SMITHKLINE BEECHAM PLC
    Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • HEGG, Lisa, Anne
    Devon, PA 19333 (US)
  • STERNER, Therese, Anne
    Devon, PA 19333 (US)
  • NURSE, Kelvin, C.
    Yardley, PA 19067 (US)

(74) Representative: Mallalieu, Catherine Louise 
D. Young & Co., 21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)

   


(54) METHODS OF MODULATING ACTIVITY OF PROKARYOTIC RIBOSOMES