(19)
(11) EP 1 181 361 A2

(12)

(88) Date of publication A3:
08.02.2001

(43) Date of publication:
27.02.2002 Bulletin 2002/09

(21) Application number: 00925239.6

(22) Date of filing: 26.04.2000
(51) International Patent Classification (IPC)7: C12N 15/11, C07K 14/82, A61K 31/70, A61K 48/00, A61P 35/00
(86) International application number:
PCT/EP0003/708
(87) International publication number:
WO 0066/724 (09.11.2000 Gazette 2000/45)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 30.04.1999 GB 9910119

(71) Applicant: Universität Zürich
8006 Zürich (CH)

(72) Inventors:
  • ZANGEMEISTER-WITTKE, Uwe
    D-79801 Hohentengen (DE)
  • LÜDKE, Gerd
    D-71126 Gäufelden (DE)
  • HUESKEN, Dieter
    D-79102 Freiburg i-Br. (DE)

(74) Representative: Blum, Rudolf Emil Ernst 
c/o E. Blum & Co Patentanwälte Vorderberg 11
8044 Zürich
8044 Zürich (CH)

   


(54) OLIGONUCLEOTIDE DERIVATIVES DIRECTED AGAINST HUMAN BCL-XL AND HUMAN BCL-2 MRNA