C7 ESTER SUBSTITUTED TAXANES AS ANTITUMOR AGENTS

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EP 1 183 253 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	07.01.2009 Bulletin 2009/02

(45)	Mention of the grant of the patent:
	21.05.2008 Bulletin 2008/21

(21)	Application number: 01905349.5

(22)	Date of filing: 02.02.2001

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International Patent Classification (IPC):

C07D 407/12^(2006.01)
A61P 35/00^(2006.01)

A61K 31/335^(2006.01)

(86)	International application number:
	PCT/US2001/003385

(87)	International publication number:
	WO 2001/057027 (09.08.2001 Gazette 2001/32)

(54)	C7 ESTER SUBSTITUTED TAXANES AS ANTITUMOR AGENTS C7-TAXANESTER ALS ANTITUMORMITTEL TAXANES SUBSTITUES PAR ESTER EN C7 UTILISES COMME AGENTS ANTICANCEREUX

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	LT LV SI

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Priority:

02.02.2000 US 179794 P

(43)	Date of publication of application:
	06.03.2002 Bulletin 2002/10

(73)	Proprietor: Florida State University Research Foundation, Inc.
	Tallahassee, FL 32310 (US)

(72)	Inventor:
	HOLTON, Robert, A., Florida State University Tallahassee, FL 32306-2763 (US)

(74)	Representative: Maiwald, Walter
	Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3 80335 München 80335 München (DE)

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References cited: :

WO-A-00/01366
WO-A-97/44026
US-A- 5 415 869

WO-A-01/25223
WO-A-97/44063

J. DUBOIS ET AL.: "Fluorescent and Biotinylated Analogues of Docetaxel: Synthesis and Biological Evaluation" BIOORG. MED. CHEM., vol. 3, no. 10, 1995, pages 1357-1368, XP000999888
D. GUENARD ET AL.: "Effects of the Hydrophobicity of Taxoids on their Interaction with Tubulin" BIOORG. MED. CHEM., vol. 8, no. 1, 2000, pages 145-156, XP001000434
F. GUERITTE-VOEGELEIN ET AL.: "Relationships between the Structue of Taxol Analogues and Their Antimitotic Activity" J. MED. CHEM., vol. 34, no. 3, 1991, pages 992-998, XP000650581

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).