(19)

(11)

EP 1 183 258 A1

(12)

(43) Date of publication: 06.03.2002 Bulletin 2002/10 (21) Application number: 00932476.5 (22) Date of filing: 16.05.2000

(51) International Patent Classification (IPC)7: C07D 487/04, A61K 31/415 // (C07D487/04, 235:00), C07D221:00,(C07D487/04, 235:00), C07D223:00 (86) International application number: PCT/US0013/413 (87) International publication number: WO 0069/860 (23.11.2000 Gazette 2000/47)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.05.1999 US 134822 P (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)	(72) Inventors: LIU, Song Cincinnati, OH 45241 (US) PORTLOCK, David, Edward Maineville, OH 45039 (US) PONG, Schwe, Fang West Chester, OH 45069 (US) (74) Representative: Clemo, Nicholas Graham  Patent Department, Procter & Gamble Technical Centres Limited, Rusham Park, Whitehall Lane Egham, Surrey TW20 9NW Egham, Surrey TW20 9NW (GB)