(19)
(11) EP 1 183 354 A2

(12)

(88) Date of publication A3:
18.01.2001

(43) Date of publication:
06.03.2002 Bulletin 2002/10

(21) Application number: 00937682.3

(22) Date of filing: 24.05.2000
(51) International Patent Classification (IPC)7C12N 15/12, C07K 14/755, C07K 14/705, A61K 38/37, A61K 38/17, A61K 31/70, A61K 48/00
(86) International application number:
PCT/US0014/111
(87) International publication number:
WO 0071/714 (30.11.2000 Gazette 2000/48)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 24.05.1999 US 135847 P

(71) Applicant: The American National Red Cross
Falls Church, VA 22042 (US)

(72) Inventors:
  • SAENKO, Evgueni, L.
    Gaithersburg, MD 20879 (US)
  • STRICKLAND, Dudley, K.
    Olney, MD 20832 (US)

(74) Representative: Ritter, Stephen David et al
Mathys & Squire 100 Gray's Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) METHODS OF REDUCING FACTOR VIII CLEARANCE AND COMPOSITIONS THEREFOR