(19)
(11)
EP 1 183 354 A2
(12)
(88)
Date of publication A3:
18.01.2001
(43)
Date of publication:
06.03.2002
Bulletin 2002/10
(21)
Application number:
00937682.3
(22)
Date of filing:
24.05.2000
(51)
International Patent Classification (IPC)
7
:
C12N
15/12
,
C07K
14/755
,
C07K
14/705
,
A61K
38/37
,
A61K
38/17
,
A61K
31/70
,
A61K
48/00
(86)
International application number:
PCT/US0014/111
(87)
International publication number:
WO 0071/714
(
30.11.2000
Gazette 2000/48)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
24.05.1999
US 135847 P
(71)
Applicant:
The American National Red Cross
Falls Church, VA 22042 (US)
(72)
Inventors:
SAENKO, Evgueni, L.
Gaithersburg, MD 20879 (US)
STRICKLAND, Dudley, K.
Olney, MD 20832 (US)
(74)
Representative:
Ritter, Stephen David et al
Mathys & Squire 100 Gray's Inn Road
London WC1X 8AL
London WC1X 8AL (GB)
(54)
METHODS OF REDUCING FACTOR VIII CLEARANCE AND COMPOSITIONS THEREFOR