(19)
(11) EP 1 183 363 A2

(12)

(88) Date of publication A3:
26.04.2001

(43) Date of publication:
06.03.2002 Bulletin 2002/10

(21) Application number: 00925293.3

(22) Date of filing: 18.05.2000
(51) International Patent Classification (IPC)7C12N 15/31, C07K 14/245, C12N 9/04, C07K 1/113, A61K 39/02, A61K 48/00
(86) International application number:
PCT/EP0004/501
(87) International publication number:
WO 0071/723 (30.11.2000 Gazette 2000/48)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 21.05.1999 US 135395 P
28.04.2000 EP 00109270

(71) Applicants:
  • Roche Diagnostics GmbH
    68298 Mannheim (DE)
  • Bukau, Bernd
    79104 Freiburg (DE)

(72) Inventors:
  • BUKAU, Bernd
    D-79104 Freiburg (DE)
  • GOLOUBINOFF, Pierre
    93855 Jerusalem (IL)

(74) Representative: Köster, Reinhold, Dr. 
c/o Roche Diagnistics GmbH, Patentabteilung, Sandhoferstrasse 116
68298 Mannheim
68298 Mannheim (DE)

   


(54) METHODS FOR REGULATING PROTEIN CONFORMATION USING MOLECULAR CHAPERONES