(19)
(11) EP 1 185 644 A1

(12)

(43) Date of publication:
13.03.2002 Bulletin 2002/11

(21) Application number: 00930934.5

(22) Date of filing: 25.05.2000
(51) International Patent Classification (IPC)7C12N 15/12, C12N 9/64, C07K 14/435, C12Q 1/37, G01N 33/50, G01N 33/68
(86) International application number:
PCT/CA0000/620
(87) International publication number:
WO 0073/437 (07.12.2000 Gazette 2000/49)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.05.1999 US 136286 P

(71) Applicant: Merck Frosst Canada & Co.
Kirkland, Quebec H9H 3L1 (CA)

(72) Inventors:
  • XANTHOUDAKIS, Steven
    Kirkland, Québec H9H 3L1 (CA)
  • TAWA, Paul
    Kirkland, Québec H9H 3L1 (CA)
  • CASSADY, Robin
    Kirkland, Québec H9H 3L1 (CA)
  • NICHOLSON, Donald
    Kirkland, Québec H9H 3L1 (CA)

(74) Representative: Horgan, James Michael Frederic et al
Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) ASSAYS FOR CASPASE ACTIVITY USING GREEN FLUORESCENT PROTEINS