(19)
(11)
EP 1 185 650 A1
(12)
(43)
Date of publication:
13.03.2002
Bulletin 2002/11
(21)
Application number:
00942067.0
(22)
Date of filing:
14.06.2000
(51)
International Patent Classification (IPC)
7
:
C12N
15/12
,
G01N
33/68
(86)
International application number:
PCT/EP0005/457
(87)
International publication number:
WO 0078/947
(
28.12.2000
Gazette 2000/52)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
22.06.1999
EP 99112024
(71)
Applicant:
MERCK PATENT GmbH
64293 Darmstadt (DE)
(72)
Inventors:
DEN DAAS, Izaak
D-64407 Fränkisch-Crumbach (DE)
FISCHER, Viola
D-55122 Mainz (DE)
SEYFRIED, Christoph
D-64342 Seeheim (DE)
VON MELCHNER, Laurie
D-64380 Rossdorf (DE)
(54)
HEAD TRAUMA INDUCED CYTOPLASMATIC CALCIUM BINDING PROTEIN