(19)

(11)

EP 1 185 676 A2

(12)

(88) Date of publication A3: 15.02.2001 (43) Date of publication: 13.03.2002 Bulletin 2002/11 (21) Application number: 00921708.4 (22) Date of filing: 05.04.2000

(51) International Patent Classification (IPC)7: C12N 15/82 (86) International application number: PCT/US0009/010 (87) International publication number: WO 0068/370 (16.11.2000 Gazette 2000/46)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 05.05.1999 US 132582 P (71) Applicant: PIONEER HI-BRED INTERNATIONAL, INC. Des Moines, Iowa 50309 (US)	(72) Inventors: MAHAJAN, Pramod, B. Urbandale, IA 50322 (US) SHI, Jinrui Johnston, IA 50131 (US) (74) Representative: Goldin, Douglas Michael  J.A. KEMP & CO.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)