(19)

(11)

EP 1 185 688 A2

(12)

(88) Date of publication A3: 19.04.2001 (43) Date of publication: 13.03.2002 Bulletin 2002/11 (21) Application number: 00936818.4 (22) Date of filing: 27.05.2000

(51) International Patent Classification (IPC)7: C12Q 1/34, C12Q 1/37, C12Q 1/44, C12Q 1/40 (86) International application number: PCT/EP0004/855 (87) International publication number: WO 0075/360 (14.12.2000 Gazette 2000/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 04.06.1999 GB 9913051 (71) Applicant: CAMBRIDGE LIFE SCIENCES PLC ElyCambridgeshire CB7 4DT (GB)	(72) Inventors: KRAUSE, Steffi Sheffield S5 7DU (GB) SUMNER, Claire DarwenLancashire BB3 3LU (GB) (74) Representative: Harrison Goddard Foote  31 St Saviourgate York Y01 8NQ York Y01 8NQ (GB)