REPORTER MOLECULES AND METHODS FOR ASSAYING HIGH SPECIFICITY PROTEASE ACTIVITY

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EP 1 185 873 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 2 (W2 B1)

(48)	Corrigendum issued on:
	25.01.2006 Bulletin 2006/04

(45)	Mention of the grant of the patent:
	28.09.2005 Bulletin 2005/39

(21)	Application number: 00936829.1

(22)	Date of filing: 26.05.2000

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International Patent Classification (IPC):

G01N 33/68^(1980.01)
C12Q 1/37^(1990.01)

G01N 33/50^(1980.01)

(86)	International application number:
	PCT/EP2000/004923

(87)	International publication number:
	WO 2000/073802 (07.12.2000 Gazette 2000/49)

(54)	REPORTER MOLECULES AND METHODS FOR ASSAYING HIGH SPECIFICITY PROTEASE ACTIVITY REPORTERVERBINDUNGEN UND VERFAHREN ZUR AUFFINDUNG VON HOCHSPEZIFISCHE PROTEASEAKTIVITÄT MOLECULES REPORTEURS ET PROCEDES PERMETTANT D'EVALUER L'ACTIVITE PROTEASIQUE A HAUTE SPECIFICITE

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

26.05.1999 EP 99201659

(43)	Date of publication of application:
	13.03.2002 Bulletin 2002/11

(73)	Proprietor: Tibotec BVBA
	2800 Mechelen (BE)

(72)	Inventors:
	VAN ACKER, Koenraad, Lodewijk, August B-9140 Temse (BE) DIERYNCK, Inge B-2610 Wilrijk (BE) PAUWELS, Rudi, Wilfried, Jan B-2820 Bonheiden (BE)

(74)	Representative: Daelemans, Frank F.R.
	Tibotec-Virco N.V., General De Wittelaan L11 B3 B-2800 Mechelen B-2800 Mechelen (BE)

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References cited: :

WO-A-94/13818
WO-A-99/18856

WO-A-98/45704

GEORGET ET AL: "Trafficking of hte androgen receptor in living cells with fused green fluorescent protein-androgen receptor" MOLECULAR AND CELLULAR ENDOCRINOLOGY,NL,AMSTERDAM, vol. 129, no. 129, 25 April 1997 (1997-04-25), pages 17-26, XP002108100 ISSN: 0303-7207
GALBIATI ET AL: "The dually acylated NH2-terminal domain of Gi1.alpha. is sufficient to target a green fluorescent protein reporter to caveolin-enriched plasma membrane domains. Palmitoylation of caveolin-1 is required for the recognition of dually acylated G-protein.alpha. subunits in vivo" JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 274, no. 9, 26 February 1999 (1999-02-26), pages 5843-5850, XP002108099 ISSN: 0021-9258
SAKAI ET AL: "Translocation of protein kinase C-gamma and epsilon - Direct visualization in living cells using fusion protein with green fluorescent protein" THE JOURNAL OF CELL BIOLOGY,US,ROCKEFELLER UNIVERSITY PRESS, 1997, XP002078902 ISSN: 0021-9525

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).