STRUCTURE-BASED DESIGN OF COMPOUNDS THAT INHIBIT DETRIMENTAL CYTOTOXIC T LYMPHOCYTE RESPONSES - Patent 1187625

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EP 1 187 625 A1

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(43)	Date of publication:
	20.03.2002 Bulletin 2002/12

(21)	Application number: 00932013.6

(22)	Date of filing: 02.05.2000

(51)	International Patent Classification (IPC)⁷: A61K 38/08, C12P 21/00

(86)	International application number:
	PCT/US0011/902

(87)	International publication number:
	WO 0066/146 (09.11.2000 Gazette 2000/45)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

04.05.1999 US 132361 P
20.08.1999 US 150150 P
01.11.1999 US 162632 P

(71)	Applicant: Philadelphia Health and Education Corporation
	Philadelphia, PA 19102 (US)

(72)	Inventors:
	JAMESON, Bradford, A. Huntingdon Valley, PA 19006 (US) TRETIAKOVA, Anna Philadelphia, PA 19147 (US)

(74)	Representative: Suèr, Steven Johannes et al
	Ablett & Stebbing,Caparo House,101-103 Baker Street London W1M 1FD London W1M 1FD (GB)

(54)	STRUCTURE-BASED DESIGN OF COMPOUNDS THAT INHIBIT DETRIMENTAL CYTOTOXIC T LYMPHOCYTE RESPONSES