(19)
(11) EP 1 187 798 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
25.10.2006 Bulletin 2006/43

(45) Mention of the grant of the patent:
14.06.2006 Bulletin 2006/24

(21) Application number: 99973927.9

(22) Date of filing: 04.11.1999
(51) International Patent Classification (IPC): 
C07B 53/00(2006.01)
 C07C 41/48(2006.01)
(86) International application number:
PCT/EP1999/008446
(87) International publication number:
WO 2001/000545 (04.01.2001 Gazette 2001/01)

(54)

PRODUCTION OF OPTICALLY ACTIVE ALPHA-HYDROXYACETALS

HERSTELLUNG VON OPTISCH AKTIVEN ALPHA-HYDROXYACETALEN

PRODUCTION DE ALPHA-HYDROXYACETALS OPTIQUEMENT ACTIFS

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 23.06.1999 CH 117099

(43) Date of publication of application:
20.03.2002 Bulletin 2002/12

(73) Proprietor: Solvias AG
4057 Basel (CH)

(72) Inventor:
  • STUDER, Martin
    CH-4054 Basel (CH)

(74) Representative: Dannappel, Hans-Jochen et al
Solvias AG Patents Erlenstrasse 1
4058 Basel
4058 Basel (CH)


(56) References cited: : 
   
  • B. T. CHO: "Asymmetric reduction of alpha-keto acetals with potassium 9-O-(1,2-isopropylidene-5-deoxy-D-xylofura nosyl)-9-boratabicyclo[3.3.1]nonane. Enantioselective synthesis of alpha-hydroxy acetals with high optical purities" TETRAHEDRON: ASYMMETRY., vol. 5, no. 7, 1994, pages 1147-1150, XP002131085 OXFORD GB cited in the application
  • H. TAKAHASHI: "Highly effective catalytic asymmetric hydrogenations of alpha-keto esters and an alpha-keto acetal with new neutral chiral pyrrolidinebisphosphine-rhodium complexes" CHEMISTRY LETTERS, no. 5, May 1987 (1987-05), pages 855-858, XP002131086 TOKYO JP cited in the application
  • H. U. BLASER: "Enantioselective hydrogenation of alpha-ketoesters with cinchona-modified platinum catalysts: effect of acidic and basic solvents and additives" JOURNAL OF MOLECULAR CATALYSIS, vol. 68, 1991, pages 215-222, XP000870037 cited in the application
  • M. STUDER: "Hydrogenation of butane-2,3-dione with heterogeneous cinchona modified platinum catalysts: a combination of an enantioselective reaction and kinetic resolution" JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, no. 9, 7 May 1998 (1998-05-07), pages 1053-1054, XP002131087 LETCHWORTH GB cited in the application
  • M. STRUDER: "Enantioselective hydrogenation of alpha-keto acetals with cinchona modified Pt catalyst" JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, no. 17, 7 September 1999 (1999-09-07), pages 1727-1728, XP002131088 LETCHWORTH GB
   
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