(19)

(11)

EP 1 187 910 A1

(12)

(43) Date of publication: 20.03.2002 Bulletin 2002/12 (21) Application number: 00921952.8 (22) Date of filing: 06.04.2000

(51) International Patent Classification (IPC)7: C12N 5/04, C12N 15/09, C12N 15/29, C12N 15/63, C12N 15/82, A01H 5/00 (86) International application number: PCT/US0009/465 (87) International publication number: WO 0063/347 (26.10.2000 Gazette 2000/43)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.04.1999 US 129593 P (71) Applicant: WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION Pullman, WA 99164-1802 (US)	(72) Inventors: RYAN, Clarence, A. Pullman, WA 99163-4607 (US) CARDENAS, Martha, O. Pullman, WA 99163 (US) (74) Representative: Cornish, Kristina Victoria Joy et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)