(19)

(11)

EP 1 190 051 A2

(12)

(88) Date of publication A3: 17.01.2002 (43) Date of publication: 27.03.2002 Bulletin 2002/13 (21) Application number: 00942880.6 (22) Date of filing: 16.06.2000

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 5/10, C07K 14/47, C07K 14/705, C07K 16/18, C07K 16/28, C12Q 1/68, A61K 38/17, G01N 33/50, A01K 67/027 (86) International application number: PCT/US0016/668 (87) International publication number: WO 0078/953 (28.12.2000 Gazette 2000/52)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 17.06.1999 US 139923 P 10.08.1999 US 148177 P 18.08.1999 US 149357 P 28.10.1999 US 162287 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: LAL, Preeti Santa Clara, CA 95054 (US) YANG, Junming San Jose, CA 95129 (US) YUE, Henry Sunnyvale, CA 94087 (US) HILLMAN, Jennifer, L. Mountain View, CA 94040 (US) TANG, Y., Tom San Jose, CA 95118 (US) BANDMAN, Olga Mountain View, CA 94043 (US) BURFORD, Neil Durham, CT 06422 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) AZIMZAI, Yalda Hayward, CA 94545 (US) LU, Dyung, Aina, M. San Jose, CA 95136 (US) AU-YOUNG, Janice Brisbane, CA 94005 (US) PATTERSON, Chandra Menlo Park, CA 94025 (US) (74) Representative: Wright, Simon Mark et al J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)