(19)
(11) EP 1 191 945 A1

(12)

(43) Date of publication:
03.04.2002 Bulletin 2002/14

(21) Application number: 00941311.3

(22) Date of filing: 09.06.2000
(51) International Patent Classification (IPC)7: A61K 48/00, A61K 39/395, A61K 38/00, C12Q 1/68, C07H 21/04, C07H 21/02, G01N 33/53
(86) International application number:
PCT/US0015/911
(87) International publication number:
WO 0076/552 (21.12.2000 Gazette 2000/51)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 11.06.1999 US 138733 P
10.10.1999 US 160441 P
20.01.2000 US 489973

(71) Applicant: Baylor College of Medicine
Houston, TX 77030 (US)

(72) Inventors:
  • KARSENTY, Gerard
    Houston, TX 77005 (US)
  • DUCY, Patricia
    Houston, TX 77098 (US)
  • AMLING, Michael
    D-22607 Hamburg (DE)

(74) Representative: Silveston, Judith et al
ABEL & IMRAY20 Red Lion Street
London, WC1R 4PQ
London, WC1R 4PQ (GB)

   


(54) METHODS AND COMPOSITIONS FOR CONTROL OF BONE FORMATION VIA MODULATION OF LEPTIN ACTIVITY