(19)
(11) EP 1 192 178 A2

(12)

(88) Date of publication A3:
05.07.2001

(43) Date of publication:
03.04.2002 Bulletin 2002/14

(21) Application number: 00946770.5

(22) Date of filing: 08.06.2000
(51) International Patent Classification (IPC)7C07K 7/00
(86) International application number:
PCT/US0015/020
(87) International publication number:
WO 0078/795 (28.12.2000 Gazette 2000/52)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 21.06.1999 US 140362 P

(71) Applicant: ELI LILLY AND COMPANY
Indianapolis, Indiana 46285 (US)

(72) Inventors:
  • KULANTHAIVEL, Palaniappan
    Carmel, IN 46032 (US)
  • VASUDEVAN, Venkatraghavan
    Indianapolis, IN 46280 (US)

(74) Representative: Burnside, Ivan John et al
Eli Lilly and Company LimitedLilly Research CentreErl Wood Manor
Windlesham, Surrey GU20 6PH
Windlesham, Surrey GU20 6PH (GB)

   


(54) RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1)