(19)
(11) EP 1 192 281 A2

(12)

(88) Date of publication A3:
16.08.2001

(43) Date of publication:
03.04.2002 Bulletin 2002/14

(21) Application number: 00941641.3

(22) Date of filing: 22.06.2000
(51) International Patent Classification (IPC)7C12Q 1/68
(86) International application number:
PCT/US0017/173
(87) International publication number:
WO 0104/354 (18.01.2001 Gazette 2001/03)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 07.07.1999 US 142857 P

(71) Applicant: REGENERON PHARMACEUTICALS, INC.
Tarrytown, NY 10591-6707 (US)

(72) Inventors:
  • GLASS, David, J.
    Cortlandt Manor, NY 10566 (US)
  • ROMMEL, Christian
    1227 Geneva (CH)
  • YANCOPOULOS, George, D.
    Yorktown Heights, NY 10598 (US)

(74) Representative: Duckworth, Timothy John 
J.A. Kemp & Co.,14 South Square,Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) USE OF RAS INHIBITORS FOR INHIBITING MUSCLE ATROPHY