(19)

(11)

EP 1 196 026 A1

(12)

(43) Date of publication: 17.04.2002 Bulletin 2002/16 (21) Application number: 00939730.8 (22) Date of filing: 08.06.2000

(51) International Patent Classification (IPC)7: A01K 67/00, A01K 33/00, G01N 33/00 (86) International application number: PCT/US0015/880 (87) International publication number: WO 0076/308 (21.12.2000 Gazette 2000/51)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 14.06.1999 US 332522 15.03.2000 US 189700 P (71) Applicant: Exelixis, Inc. South San Francisco, CA 94080 (US)

(72) Inventors: COSTA, Michael, A. San Francisco, CA 94314 (US) DOBERSTEIN, Stephen, Kohl San Francisco, CA 94107 (US) ELSON, Sarah San Francisco, CA 94110 (US) FERGUSON, Kimberly, Carr Pacifica, CA 94044 (US) HOMBURGER, Sheila, Akiko Oakland, CA 94611 (US) EBENS, Allen, James, Jr. San Francisco, CA 94122 (US) KEEGAN, Kevin, Patrick San Leandro, CA 94579 (US) STOUT, Thomas, J. San Francisco, CA 94131 (US) (74) Representative: McNally, Roisin et al Murgitroyd & Company165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)