(19)

(11)

EP 1 196 165 A2

(12)

(88) Date of publication A3: 14.06.2001 (43) Date of publication: 17.04.2002 Bulletin 2002/16 (21) Application number: 00946187.2 (22) Date of filing: 21.07.2000

(51) International Patent Classification (IPC)7: A61K 31/397, A61P 39/00, A61P 25/00, A61P 25/28, A61P 27/02 (86) International application number: PCT/GB0002/817 (87) International publication number: WO 0107/022 (01.02.2001 Gazette 2001/05)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.07.1999 GB 9917384 (71) Applicant: VERNALIS RESEARCH LIMITED Winnersh,Wokingham RG41 5UA (GB)	(72) Inventor: SNAPE, Mike, Frederick Wokingham RG41 5UA (GB) (74) Representative: Cockerton, Bruce Roger et al Carpmaels & Ransford,43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)