(19)
(11) EP 1 196 546 A2

(12)

(88) Date of publication A3:
07.06.2001

(43) Date of publication:
17.04.2002 Bulletin 2002/16

(21) Application number: 00945316.8

(22) Date of filing: 11.07.2000
(51) International Patent Classification (IPC)7C12N 9/54, C11D 3/386
(86) International application number:
PCT/US0018/853
(87) International publication number:
WO 0107/576 (01.02.2001 Gazette 2001/05)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.07.1999 US 144977 P

(71) Applicant: THE PROCTER & GAMBLE COMPANY
Cincinnati,Ohio 45202 (US)

(72) Inventors:
  • LAUGHLIN, Leo, Timothy, II
    Mason, OH 45040 (US)
  • RUBINGH, Donn, Nelton
    Cincinnati, OH 45247 (US)
  • WEISGERBER, David, John
    Cincinnati, OH 45239 (US)
  • CORREA, Paul, Elliott
    Cincinnati, OH 45252 (US)

(74) Representative: Canonici, Jean-Jacques et al
Procter & Gamble European Technical Center N.V.Temselaan 100
1853 Strombeek-Bever
1853 Strombeek-Bever (BE)

   


(54) INTRAMOLECULARLY CROSS-LINKED SUBTILISIN PROTEASES HAVING REDUCED IMMUNOGENICITY