(19)
(11) EP 1 196 613 A1

(12)

(43) Date of publication:
17.04.2002 Bulletin 2002/16

(21) Application number: 00939961.9

(22) Date of filing: 16.06.2000
(51) International Patent Classification (IPC)7C12N 15/69
(86) International application number:
PCT/US0016/767
(87) International publication number:
WO 0078/977 (28.12.2000 Gazette 2000/52)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 18.06.1999 US 140287 P

(71) Applicant: Aventis Pharmaceuticals Inc.
Bridgewater, NJ 08807-0800 (US)

(72) Inventors:
  • GROSSMAN, Trudy
    Lexington, MA 02420 (US)
  • MACNEIL, Ian
    Milton, MA 02186 (US)
  • AUGUST, Paul
    Danville, NH 03819 (US)

(74) Representative: Bouvet, Philippe 
Aventis-Pharma S.A.,20 Avenue Raymond Aron
92165 Antony Cedex
92165 Antony Cedex (FR)

   


(54) NOVEL VECTORS FOR IMPROVING CLONING AND EXPRESSION IN LOW COPY NUMBER PLASMIDS