OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES - Patent 1198592

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EP 1 198 592 A1

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(43)	Date of publication:
	24.04.2002 Bulletin 2002/17

(21)	Application number: 00947043.6

(22)	Date of filing: 05.07.2000

(51)	International Patent Classification (IPC)⁷: C12Q 1/68, C12P 19/34, C07H 21/00, C07H 21/02, C07H 21/04, A01N 43/04

(86)	International application number:
	PCT/US0018/415

(87)	International publication number:
	WO 0102/608 (11.01.2001 Gazette 2001/02)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

06.07.1999 US 348106

(71)	Applicant: ISIS PHARMACEUTICALS, INC.
	Carlsbad, CA 92008 (US)

(72)	Inventors:
	MANOHARAN, Muthiah Carlsbad, CA 92009 (US) COOK, Phillip, Dan Fallbrook, CA 92028 (US)

(74)	Representative: Hallybone, Huw George et al
	Carpmaels and Ransford,43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

(54)	OLIGONUCLEOTIDES INCORPORATING BOTH 2-AMINOADENINE AND 5-SUBSTITUTED PYRIMIDINES