(19)
(11) EP 1 200 469 A2

(12)

(88) Date of publication A3:
23.08.2001

(43) Date of publication:
02.05.2002 Bulletin 2002/18

(21) Application number: 00951682.4

(22) Date of filing: 25.07.2000
(51) International Patent Classification (IPC)7C07K 14/47, C07K 16/18, G01N 33/68
(86) International application number:
PCT/GB0002/873
(87) International publication number:
WO 0107/479 (01.02.2001 Gazette 2001/05)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.07.1999 GB 9917491
30.07.1999 GB 9917878

(71) Applicant: IMPERIAL COLLEGE INNOVATIONS LIMITED
London SW7 2AZ (GB)

(72) Inventors:
  • COLLINGE, JohnMRC Prion Unit Dep.of Neurogenetics
    Norfolk Placelondon W2 1PG (GB)
  • CLARKE, Anthony, RusselMRC Prion Unit
    Norfolk PlaceLondon W2 1PG (GB)
  • WALTHO, Jonathan, Peter14 Rock Cottages
    Derbyshire SK17 8SY (GB)
  • JACKSON, Graham, StuartMRC Prion Unit
    Norfolk PlaceLondon W2 1PG (GB)
  • HOSSZU, Laszlo, Luis, PereiraMRC Prion Unit
    Norfolk PlaceLondon W2 1PG (GB)

(74) Representative: Thomas, Philip John Duval 
Eric Potter Clarkson,Park View House,58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) FRAGMENTS OF CELLULAR PRION PROTEIN AND METHODS USEFUL IN THE DIAGNOSIS AND TREATMENT OF PRION DISEASES