(19)
(11) EP 1 202 626 A1

(12)

(43) Date of publication:
08.05.2002 Bulletin 2002/19

(21) Application number: 00947506.2

(22) Date of filing: 19.07.2000
(51) International Patent Classification (IPC)7: A01N 43/16, A01N 43/36, A01N 43/40, A01N 43/42, A01N 43/76, A01N 43/78, A61K 31/35, A61K 31/40, A61K 31/42, A61K 31/44, A61K 31/425
(86) International application number:
PCT/US0019/626
(87) International publication number:
WO 0105/230 (25.01.2001 Gazette 2001/04)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 20.07.1999 US 144644 P
02.08.1999 US 365034
04.08.1999 US 147226 P
04.08.1999 US 366891
18.07.2000 WO PCT/US00/19573

(71) Applicant: Merck & Co., Inc.
Rahway,New Jersey 07065-0907 (US)

(72) Inventors:
  • TATA, James, R.
    Rahway, NJ 07065-0907 (US)
  • CHAREST, Mark
    Rahway, NJ 07065-0907 (US)
  • LU, Zhijian
    Rahway, NJ 07065-0907 (US)
  • RAGHAVAN, Subharekha
    Rahway, NJ 07065-0907 (US)
  • HUENING, Tracy
    Rahway, NJ 07065-0907 (US)
  • RANO, Thomas
    Rahway, NJ 07065-0907 (US)

(74) Representative: Horgan, James Michael Frederic 
Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) ALPHA-HYDROXY-GAMMA-[[(CARBOCYCLIC-OR HETEROCYCLIC-SUBSTITUTED)AMINO]CARBONYL]ALKANAMIDE DERIVATIVES AND USES THEREOF