(19)

(11)

EP 1 202 723 A2

(12)

(88) Date of publication A3: 20.09.2001 (43) Date of publication: 08.05.2002 Bulletin 2002/19 (21) Application number: 00949799.1 (22) Date of filing: 07.08.2000

(51) International Patent Classification (IPC)7: A61K 31/14, A61K 31/40, A61K 31/35, A61K 31/445, A61K 31/535 (86) International application number: PCT/GB0003/032 (87) International publication number: WO 0110/427 (15.02.2001 Gazette 2001/07)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.08.1999 GB 9918760 (71) Applicant: Arakis Limited Nr. Saffron Walden,Essex CB10 1XL (GB)	(72) Inventors: COLLIER, Paula,c/o Celltech R&D Ltd. Cambridge CB1 6GS (GB) MANALLACK, David Thomas,c/o Celltech R&D Ltd. Cambridge CB1 6GS (GB) BANNISTER, Robin Mark,c/o Arakis Ltd. Nr.Safron Walden,Essex CB101XL (GB) (74) Representative: Perry, Robert Edward  GILL JENNINGS & EVERYBroadgate House7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)