(19)
(11) EP 1 204 656 A2

(12)

(88) Date of publication A3:
17.05.2001

(43) Date of publication:
15.05.2002 Bulletin 2002/20

(21) Application number: 00950223.8

(22) Date of filing: 17.07.2000
(51) International Patent Classification (IPC)7C07D 333/64, A61K 31/4535, A61P 5/32
(86) International application number:
PCT/US0016/333
(87) International publication number:
WO 0109/116 (08.02.2001 Gazette 2001/06)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 29.07.1999 US 146286 P
06.08.1999 US 147570 P
19.08.1999 US 149773 P

(71) Applicant: ELI LILLY AND COMPANY
Indianapolis, Indiana 46285 (US)

(72) Inventors:
  • BUSH, Julie, Kay
    Fishers, IN 46038 (US)
  • CONRAD, Preston, Charles
    Indianapolis, IN 46236 (US)
  • FLOM, Merlyn, Gerard
    Noblesville, IN 46060 (US)
  • LUKE, Wayne, Douglas
    West Lafayette, IN 47906 (US)

(74) Representative: Vaughan, Jennifer Ann et al
Eli Lilly and Company LimitedLilly Research CentreErl Wood Manor
Windlesham, Surrey GU20 6PH
Windlesham, Surrey GU20 6PH (GB)

   


(54) A CRYSTALLINE FORM OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL) ETHOXY] PHENOXY)-2-(4-METHOXYPHENYL) BENZO[B]THIOPHENE HYDROCHLORIDE