(19)

(11)

EP 1 204 681 A2

(12)

(88) Date of publication A3: 12.07.2001 (43) Date of publication: 15.05.2002 Bulletin 2002/20 (21) Application number: 00957562.2 (22) Date of filing: 18.08.2000

(51) International Patent Classification (IPC)7: C07K 14/52, C12N 15/16, C12N 15/62, C12N 5/10, C07K 16/24 (86) International application number: PCT/US0022/714 (87) International publication number: WO 0112/665 (22.02.2001 Gazette 2001/08)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 18.08.1999 US 376826 (71) Applicant: ZymoGenetics, Inc. Seattle, WA 98102 (US)	(72) Inventor: CONKLIN, Darrell, C. Seattle, WA 98102 (US) (74) Representative: Dean, John Paul et al Withers & Rogers,Goldings House,2 Hays Lane London SE1 2HW London SE1 2HW (GB)