(19)

(11)

EP 1 204 852 A1

(12)

(43) Date of publication: 15.05.2002 Bulletin 2002/20 (21) Application number: 00942267.6 (22) Date of filing: 03.07.2000

(51) International Patent Classification (IPC)7: G01N 13/00, G01N 35/00 (86) International application number: PCT/GB0002/567 (87) International publication number: WO 0102/834 (11.01.2001 Gazette 2001/02)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.07.1999 GB 9915686 (71) Applicant: AstraZeneca UK Limited London W1Y 6LN (GB)	(72) Inventors: SHAW, John, Edward, Andrew West Drayton,Middlesex UB8 2LQ (GB) TURNER, Christopher, Matthew Uxbridge,Middlesex UB8 2LQ (GB) LAW, Brian Macclesfield,Cheshire SK10 4TG (GB) (74) Representative: Bill, Kevin  AstraZeneca,Global Intellectual Property, Patents,P.O. Box 272, Mereside,Alderley Park Macclesfield, Cheshire SK10 4GR Macclesfield, Cheshire SK10 4GR (GB)