(19)

(11)

EP 1 206 250 A2

(12)

(88) Date of publication A3: 25.05.2001 (43) Date of publication: 22.05.2002 Bulletin 2002/21 (21) Application number: 00954802.5 (22) Date of filing: 29.08.2000

(51) International Patent Classification (IPC)7: A61K 9/50, A61K 9/16, A61K 9/28, A61K 9/20, A61K 9/48 (86) International application number: PCT/GB0003/309 (87) International publication number: WO 0113/898 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 26.08.1999 US 150880 P 26.08.1999 US 150891 P 26.08.1999 US 151211 P (71) Applicant: ELAN CORPORATION, Plc Dublin 2 (IE)

(72) Inventors: ANDINA, Christian,Elan Pharm. Technologies Athlone,County Westmeath (IE) FANNING, Niall,Elan Pharm. Technologies Athlone,County Westmeath (IE) PALMER, Fiona,Elan Pharm. Technologies Athlone,County Westmeath (IE) STARK, Paul,Elan Pharm. Technologies Athlone,County Westmeath (IE) (74) Representative: Stoner, Gerard Patrick et al MEWBURN ELLISYork House23 Kingsway London WC2B 6HP London WC2B 6HP (GB)