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EP 1 206 450 A1

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(43) Date of publication: 22.05.2002 Bulletin 2002/21 (21) Application number: 00955831.3 (22) Date of filing: 23.08.2000

(51) International Patent Classification (IPC)7: C07D 207/26, C07D 261/18, C07D 413/12, C07K 5/02 (86) International application number: PCT/US0023/033 (87) International publication number: WO 0114/329 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.08.1999 US 150358 P (71) Applicant: AGOURON PHARMACEUTICALS, INC. La Jolla, CA 93057-1020 (US)

(72) Inventors: TIAN, Qingping San Diego, CA 92129 (US) NAYYAR, Naresh, K. San Diego, CA 92129 (US) BABU, Srinivasan San Diego, CA 92121 (US) TAO, Junhua San Diego, CA 92129 (US) MORAN, Terence, Jarold San Diego, CA 92128 (US) DAGNINO, Raymond, Jr. El Cajon, CA 92019 (US) MITCHELL, Lennert, J. Chula Vista, CA 91910 (US) REMARCHUK, Travis, Paul Irvine, CA 92612 (US) MELNICK, Michael Joseph,Parke-Davis Ann Arbor, MI 48105 (US) BENDER, Steven, Lee Oceanside, CA 92054 (US) (74) Representative: Teipel, Stephan et al Lederer & KellerPatentanwältePrinzregentenstrasse 16 80538 München 80538 München (DE)