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(11)

EP 1 206 470 A2

(12)

(88) Date of publication A3: 30.08.2001 (43) Date of publication: 22.05.2002 Bulletin 2002/21 (21) Application number: 00955830.5 (22) Date of filing: 23.08.2000

(51) International Patent Classification (IPC)7: C07D 413/12, C07D 261/18, C07C 309/65, C07C 303/28, C07C 69/732, C07C 59/56, C07C 271/22, C07C 229/36, C07C 51/347, C12P 17/14, C12P 7/42, C12P 1/00 (86) International application number: PCT/US0023/032 (87) International publication number: WO 0114/576 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.08.1999 US 150365 P (71) Applicant: AGOURON PHARMACEUTICALS, INC. La Jolla, CA 93057-1020 (US)

(72) Inventors: TAO, Junhua San Diego, CA 92129 (US) BABU, Srinivasan San Diego, CA 92121 (US) DAGNINO, Raymond, Jr. El Cajon, CA 92019 (US) TIAN, Qingping San Diego, CA 92129 (US) REMARCHUK, Travis, Paul Irvine, CA 92612 (US) MCGEE, Kevin, Scott San Diego, CA 92126 (US) NAYYAR, Naresh, K. San Diego, CA 92129 (US) MORAN, Terence, Jarold San Diego, CA 92128 (US) (74) Representative: Keller, Günter, Dr. et al Lederer & KellerPatentanwältePrinzregentenstrasse 16 80538 München 80538 München (DE)