(19)

(11)

EP 1 206 553 A2

(12)

(88) Date of publication A3: 25.10.2001 (43) Date of publication: 22.05.2002 Bulletin 2002/21 (21) Application number: 00957506.9 (22) Date of filing: 16.08.2000

(51) International Patent Classification (IPC)7: C12N 15/61, C12N 9/90, C07K 16/40, C12Q 1/68, A61K 38/52, A01K 67/027, G01N 33/50 (86) International application number: PCT/US0022/518 (87) International publication number: WO 0112/790 (22.02.2001 Gazette 2001/08)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 17.08.1999 US 149388 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: BANDMAN, Olga Mountain View, CA 94043 (US) LU, Dyung, Aina, M. San Jose, CA 95136 (US) YUE, Henry Sunnyvale, CA 94087 (US) TRAN, Bao Santa Clara, CA 95051 (US) HILLMAN, Jennifer, L. Mountain View, CA 94040 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) LAL, Preeti Santa Clara, CA 95054 (US) TANG, Y., Tom San Jose, CA 95118 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.,14 South Square,Gray's Inn London, WC1R 5JJ London, WC1R 5JJ (GB)