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(11)

EP 1 208 193 A1

(12)

(43) Date of publication: 29.05.2002 Bulletin 2002/22 (21) Application number: 00953983.4 (22) Date of filing: 11.08.2000

(51) International Patent Classification (IPC)7: C12N 9/02, C12N 15/52 (86) International application number: PCT/US0022/038 (87) International publication number: WO 0112/791 (22.02.2001 Gazette 2001/08)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 12.08.1999 US 148850 P (71) Applicant: Maxygen, Inc. Redwood City, CA 94063 (US)	(72) Inventors: SELIFONOV, Sergey A. Los Altos, CA 94024 (US) NEWMAN, Lisa, M. Sunnyvale, CA 94086 (US) (74) Representative: Kjerrumgaard, Lars Bo et al Maxygen ApS,Patent Department,Agern Alle 1 2970 Horsholm 2970 Horsholm (DK)