(19)

(11)

EP 1 210 320 A1

(12)

(43) Date of publication: 05.06.2002 Bulletin 2002/23 (21) Application number: 00943699.9 (22) Date of filing: 11.07.2000

(51) International Patent Classification (IPC)7: C07C 235/04, C07C 237/04, C07C 229/18, A61K 31/165, A61K 31/222 (86) International application number: PCT/DK0000/385 (87) International publication number: WO 0105/746 (25.01.2001 Gazette 2001/04)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.07.1999 US 144166 P (71) Applicant: LEO PHARMACEUTICAL PRODUCTS LTD. A/S(LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) 2750 Ballerup (DK)	(72) Inventor: OTTOSEN, Erik, Rytter DK-3650 Olstykke (DK) (74) Representative: Thalsoe-Madsen, Kine Birgit  Leo Pharmaceutical Products,Industriparken 55 2750 Ballerup 2750 Ballerup (DK)