(19)

(11)

EP 1 210 360 A1

(12)

(43) Date of publication: 05.06.2002 Bulletin 2002/23 (21) Application number: 00959312.0 (22) Date of filing: 23.08.2000

(51) International Patent Classification (IPC)7: C07K 5/02 (86) International application number: PCT/US0023/049 (87) International publication number: WO 0114/412 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.08.1999 US 150260 P 27.08.1999 US 151169 P 07.09.1999 US 152696 P (71) Applicant: The Regents of the University of California Oakland, CA 94607-5200 (US)	(72) Inventors: NOWICK, James, S. Irvine, CA 92612 (US) MAITRA, Santanu Irvine, CA 92612 (US) (74) Representative: Coates, Ian Harold et al Sommerville & Rushton,45 Grosvenor Road St. Albans, Hertfordshire AL1 3AW St. Albans, Hertfordshire AL1 3AW (GB)