(19)
(11) EP 1 210 365 A2

(12)

(88) Date of publication A3:
18.10.2001

(43) Date of publication:
05.06.2002 Bulletin 2002/23

(21) Application number: 00955471.8

(22) Date of filing: 11.08.2000
(51) International Patent Classification (IPC)7C07K 14/315, C12N 15/11, C12N 15/52
(86) International application number:
PCT/US0022/086
(87) International publication number:
WO 0112/803 (22.02.2001 Gazette 2001/08)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 17.08.1999 US 149313 P

(71) Applicant: Beth Israel Deaconess Medical Center, Inc.
Boston, MA 02215 (US)

(72) Inventors:
  • INOUYE, Roger, T.
    Wellesley, MA 02481 (US)
  • TORRES-VIERA, Carlos
    Urb Sorocaima,Caracas, Venezuela (VE)
  • MOELLERING, Robert
    Wellesley Hills, MA 02481-5220 (US)
  • GOLD, Howard
    Brookline, MA 02446-3489 (US)
  • ELIOPOULOS, George, M.
    Needham, MA 02494 (US)

(74) Representative: Jump, Timothy John Simon et al
Venner Shipley & Co.20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) METHODS AND COMPOSITIONS FOR RESTORING ANTIBIOTIC SUSCEPTIBILITY IN GLYCOPEPTIDE-RESISTANT ENTEROCOCCUS