(19)

(11)

EP 1 210 368 A2

(12)

(88) Date of publication A3: 25.10.2001 (43) Date of publication: 05.06.2002 Bulletin 2002/23 (21) Application number: 00961634.3 (22) Date of filing: 07.09.2000

(51) International Patent Classification (IPC)7: C07K 14/47, C07K 14/705, A61K 38/17, A61P 35/00, A61P 37/02 (86) International application number: PCT/US0024/560 (87) International publication number: WO 0118/044 (15.03.2001 Gazette 2001/11)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 08.09.1999 US 152914 P 27.09.1999 US 156257 P 29.12.1999 US 173906 P (71) Applicant: IMMUNEX CORPORATION Seattle, WA 98101-2936 (US)	(72) Inventor: SPRIGGS, Melanie, K. Seattle, WA 98119 (US) (74) Representative: Perry, Robert Edward  GILL JENNINGS & EVERYBroadgate House7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)