(19)
(11) EP 1 210 432 A2

(12)

(88) Date of publication A3:
18.10.2001

(43) Date of publication:
05.06.2002 Bulletin 2002/23

(21) Application number: 00992198.2

(22) Date of filing: 06.09.2000
(51) International Patent Classification (IPC)7C12N 15/12, A61K 48/00, A61P 19/02
(86) International application number:
PCT/US0040/823
(87) International publication number:
WO 0125/435 (12.04.2001 Gazette 2001/15)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 07.09.1999 US 152707 P

(71) Applicant: Colorado State University Research Foundation
Fort Collins,CO 80521 (US)

(72) Inventors:
  • FRISBIE, David, D.
    Fort Collins, CO 80524 (US)
  • MCILLWRAITH, Wayne, C.
    Fort Collins, CO 80524 (US)

(74) Representative: Hiebl, Inge Elisabeth 
Kraus & WeisertPatent- und RechtsanwälteThomas-Wimmer-Ring 15
80539 München
80539 München (DE)

   


(54) i IN VIVO /i TREATMENT OF JOINT DISEASE USING INTERLEUKIN-1 RECEPTOR ANTAGONISTS