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(11)

EP 1 212 076 A2

(12)

(88) Date of publication A3: 02.08.2001 (43) Date of publication: 12.06.2002 Bulletin 2002/24 (21) Application number: 00954793.6 (22) Date of filing: 24.08.2000

(51) International Patent Classification (IPC)7: A61K 38/08, A61K 38/23, C12N 5/06, A61K 35/52, A61P 15/08 // (A61K38/23, 38:06, 31:7052),(A61K38/23, 38:08, 38:06, 31:7052) (86) International application number: PCT/GB0003/292 (87) International publication number: WO 0113/932 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 26.08.1999 GB 9920262 (71) Applicant: KING'S COLLEGE LONDON London WC2R 2LS (GB)	(72) Inventor: FRASER, Lynn Repsis Herts WD3 2EW (GB) (74) Representative: Tollett, Ian et al Williams, Powell & Associates,4 St. Paul's Churchyard London EC4M 8AY London EC4M 8AY (GB)