(19)
(11) EP 1 212 101 A1

(12)

(43) Date of publication:
12.06.2002 Bulletin 2002/24

(21) Application number: 00959851.7

(22) Date of filing: 31.08.2000
(51) International Patent Classification (IPC)7A61K 49/00, A61K 31/00, A61K 45/00, A61P 9/00
(86) International application number:
PCT/US0024/251
(87) International publication number:
WO 0115/744 (08.03.2001 Gazette 2001/10)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 31.08.1999 US 387028

(71) Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
Boston, MA 02115 (US)

(72) Inventors:
  • RIDKER, Paul
    Chestnut Hill, MA 02167 (US)
  • HENNEKENS, Charles, H.
    Boca Raton, FL 33486 (US)

(74) Representative: Jump, Timothy John Simon et al
Venner Shipley & Co.20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) SYSTEMIC INFLAMMATORY MARKERS AS DIAGNOSTIC TOOLS IN THE PREVENTION OF ATHEROSCLEROTIC DISEASES