8-SUBSTITUTED-6-TRIFLUOROMETHYL-9-PYRIDO[3,2-G]QUINOLINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS - Patent 1212322

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EP 1 212 322 A2

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(88)	Date of publication A3:
	14.06.2001

(43)	Date of publication:
	12.06.2002 Bulletin 2002/24

(21)	Application number: 00957851.9

(22)	Date of filing: 25.08.2000

(51)	International Patent Classification (IPC)⁷: C07D 471/04, A61K 31/4375, A61P 5/26 // (C07D471/04, 221:00), C07D221:00

(86)	International application number:
	PCT/US0023/507

(87)	International publication number:
	WO 0116/133 (08.03.2001 Gazette 2001/10)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

27.08.1999 US 151235 P

(71)	Applicant: LIGAND PHARMACEUTICALS INCORPORATED
	San Diego,California 92121 (US)

(72)	Inventors:
	HAMANN, Lawrence, G. Solana Beach, CA 92075 (US) KONG, James San Diego, CA 92014 (US) EDWARDS, James, P. San Diego, CA 92129 (US)

(74)	Representative: Keen, Celia Mary et al
	J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)

(54)	8-SUBSTITUTED-6-TRIFLUOROMETHYL-9-PYRIDO[3,2-G]QUINOLINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS