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(11)

EP 1 212 413 A1

(12)

(43) Date of publication: 12.06.2002 Bulletin 2002/24 (21) Application number: 00957700.8 (22) Date of filing: 23.08.2000

(51) International Patent Classification (IPC)7: C12N 15/10, C07K 14/705 (86) International application number: PCT/US0023/112 (87) International publication number: WO 0114/542 (01.03.2001 Gazette 2001/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 25.08.1999 US 150747 P (71) Applicant: Genome Therapeutics Corporation Waltham, MA 02453 (US)	(72) Inventors: DENOME, Sylvia, Anne Taunton, MA 02780 (US) SWAIN, Pamela, Marie Lunenberg, MA 01462 (US) TZELLAS, Nia Medford, MA 02155 (US) (74) Representative: Müller-Boré & PartnerPatentanwälte  Grafinger Strasse 2 81671 München 81671 München (DE)