(19)

(11)

EP 1 214 049 A2

(12)

(88) Date of publication A3: 27.09.2001 (43) Date of publication: 19.06.2002 Bulletin 2002/25 (21) Application number: 00958066.3 (22) Date of filing: 07.09.2000

(51) International Patent Classification (IPC)7: A61K 7/48 (86) International application number: PCT/CA0001/031 (87) International publication number: WO 0117/484 (15.03.2001 Gazette 2001/11)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.09.1999 US 152637 P (71) Applicant: D.T.R. Dermal Therapy Research Inc. London,Ontario N5X 2N9 (CA)	(72) Inventors: SINGH, Parashu, Ram North York, Ontario M2J 3P1 (CA) PERLMUTTER, Alan, Lorne London, Ontario N5Z 2N9 (CA) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)