(19)

(11)

EP 1 214 071 A2

(12)

(88) Date of publication A3: 07.03.2002 (43) Date of publication: 19.06.2002 Bulletin 2002/25 (21) Application number: 00965127.4 (22) Date of filing: 19.09.2000

(51) International Patent Classification (IPC)7: A61K 31/4545, A61P 37/08, A61P 29/00 (86) International application number: PCT/US0025/609 (87) International publication number: WO 0121/162 (29.03.2001 Gazette 2001/13)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 22.09.1999 US 400599 (71) Applicant: SCHERING CORPORATION Kenilworth,New Jersey 07033-0530 (US)	(72) Inventor: HEITHOFF, Kim Allen Oldwick, NJ 08858-0423 (US) (74) Representative: Ritter, Stephen David et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)