(19)
(11) EP 1 214 087 A1

(12)

(43) Date of publication:
19.06.2002 Bulletin 2002/25

(21) Application number: 00951799.6

(22) Date of filing: 28.08.2000
(51) International Patent Classification (IPC)7: A61K 38/20, A61K 31/64, A61P 19/02
// A61K31:64, A61K38:20
(86) International application number:
PCT/IB0001/192
(87) International publication number:
WO 0119/390 (22.03.2001 Gazette 2001/12)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 14.09.1999 US 154010 P

(71) Applicant: Pfizer Products Inc.
Groton,Connecticut 06340 (US)

(72) Inventors:
  • LITTMAN, Bruce Henry,c/o Pfizer Inc,Central Res
    Groton, CT 06340 (US)
  • WOODWORTH, Thasia Louise Goodwin,Pfizer Inc.
    Groton,CT 06340 (US)
  • DOMBROSKI, Mark Anthony,Pfizer Inc
    Eastern Point Road,Groton, CT 06340 (US)

(74) Representative: Hayles, James Richard 
Pfizer Limited,Patents Department,Ramsgate Road
SandwichKent CT13 9NJ
SandwichKent CT13 9NJ (GB)

   


(54) COMBINATION TREATMENT WITH IL-1RA AND COMPOUNDS THAT INHIBIT IL-1 PROCESSING AND RELEASE