EMBRYONIC OR STEM-LIKE CELL LINES PRODUCED BY CROSS SPECIES NUCLEAR TRANSPLANTATION AND METHODS FOR ENHANCING EMBRYONIC DEVELOPMENT BY GENETIC ALTERATION OF DONOR CELLS OR BY TISSUE CULTURE CONDITIONS - Patent 1214404

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EP 1 214 404 A1

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(43)	Date of publication:
	19.06.2002 Bulletin 2002/25

(21)	Application number: 00966717.1

(22)	Date of filing: 14.09.2000

(51)	International Patent Classification (IPC)⁷: C12N 15/00, C12N 5/00, C12N 5/08, C12N 5/02, A61K 48/00

(86)	International application number:
	PCT/US0025/090

(87)	International publication number:
	WO 0119/977 (22.03.2001 Gazette 2001/12)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

14.09.1999 US 395368

(71)	Applicant: University of Massachusetts, a Public Institution of Higher Education of The Commonwealth of Massachusetts,
	Amherst, MA 01002 (US)

(72)	Inventors:
	ROBL, James Belchertown, MA 01007 (US) CIBELLI, Jose Amherst, MA 01002 (US) STICE, Steven, L. Belchertown, MA 01007 (US)

(74)	Representative: Daniels, Jeffrey Nicholas et al
	Page White & Farrer54 Doughty Street London WC1N 2LS London WC1N 2LS (GB)

(54)	EMBRYONIC OR STEM-LIKE CELL LINES PRODUCED BY CROSS SPECIES NUCLEAR TRANSPLANTATION AND METHODS FOR ENHANCING EMBRYONIC DEVELOPMENT BY GENETIC ALTERATION OF DONOR CELLS OR BY TISSUE CULTURE CONDITIONS