(19)

(11)

EP 1 218 742 A1

(12)

(43) Date of publication: 03.07.2002 Bulletin 2002/27 (21) Application number: 00958878.1 (22) Date of filing: 13.09.2000

(51) International Patent Classification (IPC)7: G01N 33/542, G01N 33/60, C12Q 1/48 (86) International application number: PCT/GB0003/495 (87) International publication number: WO 0120/327 (22.03.2001 Gazette 2001/12)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.09.1999 GB 9921684 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventor: WADDELL, Ian, David Macclesfield,Cheshire SK10 4TG (GB)